- Genetic diversity: Arabs are a diverse group of people, with a range of genetic variations that can impact drug metabolism and disease susceptibility. For example, Arabs have been shown to have a high prevalence of genetic variations that affect drug metabolism, such as CYP2C19 polymorphisms.
- Disease prevalence: Arabs are also known to have higher rates of certain diseases, such as diabetes and heart disease, compared to other populations. Including Arabs in clinical trials could help identify genetic and environmental factors that contribute to these disparities and lead to more effective prevention and treatment strategies.
- Cultural and environmental factors: Arabs also have unique cultural and environmental factors that could impact their health outcomes. For example, dietary habits, lifestyle factors, and exposure to certain toxins or pollutants could affect their response to drugs or susceptibility to disease.
Overall, including Arabs as a separate category in clinical trials could help improve our understanding of the unique genetic and environmental factors that affect their health outcomes and lead to more personalized and effective treatments for this population.